Product Name: Sinomenine hydrochloride
Source: Sinomenium acutum
Part Used:Vine
CAS No: 6080-33-7
Molecular Weight:365.85
Empirical Formula (Hill Notation): C19H23NO4 • HCl
Specification:98% By HPLC
Package:25Kg/Drum
Drum’s Size:36cm*36cm*52cm
Shelf Time:2 Years
Description
Sinomenine is now known to be effective in neuralgia and rheumatic diseases. That is a unique plant alkaloid, as it potently releases histamine in association with degranulation of mast cells in connective tissue, preferentially in the skin and joint capsules. The released histamine is responsible for the pharmacological actions of sinomenine, such as vasodilation, increased vascular permeability, acceleration of the thoracic and peripheral lymph flow, contraction of smooth muscles, increased peristalsis of the intestines, and stimulation of gastric acid secretion.
Specification
Product: |
Sinomenine hydrochloride |
Part Used: |
Vine |
Source: |
Sinomenium acutum |
CAS No: |
5508-58-7 |
ITEM |
SPECIFICATION |
TEST METHOD |
Physical Description |
||
Appearance |
White Powder |
Visual |
Odor |
Characteristic |
Organoleptic |
Taste |
Characteristic |
Olfactory |
Bulk Density |
50-60g/100ml |
CP2015 |
Particle Size |
95%-99% through 80 mesh |
CP2015 |
Chemical Tests |
||
Sinomenine hydrochloride |
≥98% |
HPLC |
Loss on Drying |
≤1.0% |
CP2015 (105 oC, 3 h) |
Ash |
≤1.0% |
CP2015 |
Total Heavy Metals |
≤10 ppm |
CP2015 |
Cadmium (Cd) |
≤1 ppm |
CP2015(AAS) |
Mercury (Hg) |
≤1 ppm |
CP2015(AAS) |
Lead (Pb) |
≤2 ppm |
CP2015(AAS) |
Arsenic (As) |
≤2ppm |
CP2015(AAS) |
Microbiology Control |
||
Aerobic Bacterial Count |
≤1,000 cfu/g |
CP2015 |
Total Yeast & Mold |
≤100 cfu/g |
CP2015 |
Escherichia Coli |
Negative |
CP2015 |
Salmonella |
Negative |
CP2015 |
Staphlococcus Aureus |
Negative |
CP2015 |
Function
1.With certain alkaloids analgesia calm;
2.Can be used as antitussive bureau hemp, fall blood pressure;
3.Anti-inflammatory effect of sinomenine for the release of histamine in strong;
4.Sinomenine is used to protect clinical treatment of rheumatoid arthritis and neuralgia.
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